Assessing safety, efficacy and transmission blocking properties of the new anti-malarial KAF156 combined with a new formulation of lumefantrine in children and adults with uncomplicated Plasmodium sp. malaria in West and Central Africa (WANECAM II) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Abdoulaye Djimde | Gabon, Burkina Faso, Mali, Niger
Randomized Controlled Trial to Evaluate the Safety and Immunogenicity of Recombinant Pichia Pastoris-Expressed P. Falciparum Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) Versus Tetanus Toxoid, in Healthy Malian Adult in Bandiagara African Malaria Network Trust (AMANET), Tanzania, University of Bamako, Mali | Mahamadou A. Thera | Africa, Western, Mali
Proactive Community Case Management and Child Survival: A Cluster-Randomized Controlled Trial Child Relief International Foundation, Grand Challenges Canada, Johnson & Johnson Foundation, United States Agency for International Development (USAID), University of California San Francisco (UCSF), USA, Malaria Research and Training Center (MRTC), University of Bamako, Mali | Kassoum Kayentao, Nancy S. Padian | Mali
Increasing Intermittent Preventive Treatment uptake through enhanced antenatal clinic service delivery to improve maternal and child health U.S. President’s Malaria Initiative (PMI), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Mali
Understanding the biology of Plasmodium vivax and Plasmodium ovale for the development of a field-based anti-hypnozoite drug screening model (HypnoBio) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
Clinical evaluation of AntimalarialS tri-therapy with AtovAquone-Proguanil for treatment of uncomplicated malaria in African children (ASAAP) European & Developing Countries Clinical Trials Partnership (EDCTP), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana | Oumou Maiga-Ascofare | Gabon, Benin, Burkina Faso, Guinea, Mali
Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women (PYRAPREG) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Dem. Rep. Congo, Mozambique, Burkina Faso, Gambia, Mali