Randomized Controlled Trial to Evaluate the Safety and Immunogenicity of Recombinant Pichia Pastoris-Expressed P. Falciparum Apical Membrane Antigen 1 (PfAMA-1-FVO[25-545]) Versus Tetanus Toxoid, in Healthy Malian Adult in Bandiagara African Malaria Network Trust (AMANET), Tanzania, University of Bamako, Mali | Mahamadou A. Thera | Africa, Western, Mali
Understanding the biology of Plasmodium vivax and Plasmodium ovale for the development of a field-based anti-hypnozoite drug screening model (HypnoBio) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
West Africa Malaria Initiative (WAMI) Spanish Agency for International Development Cooperation (AECID), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Ogobara Doumbo | Africa, Western
Clinical evaluation of AntimalarialS tri-therapy with AtovAquone-Proguanil for treatment of uncomplicated malaria in African children (ASAAP) European & Developing Countries Clinical Trials Partnership (EDCTP), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana | Oumou Maiga-Ascofare | Gabon, Benin, Burkina Faso, Guinea, Mali
Malaria in pregnant is a public health problem in sub Saharan countries where 11 million pregnancies are exposed to malaria infection. Plasmodium falciparum in pregnant can cause adverse maternal health and poor birth outcomes. Artemisin-based Combination Therapy (ACT) used in treatment of uncomplicated Plasmodium falciparum malaria in pregnant women has the efficacy in Africa. The…
Ex-vivo clinical candidate drug assay against field clinical isolated blood stages parasites of P. malariae and P. ovale using 10 compounds from MMV. Medicines for Malaria Venture (MMV), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ghana, Mali
Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women (PYRAPREG) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Dem. Rep. Congo, Mozambique, Burkina Faso, Gambia, Mali