2010 Dec – 2012 Jun | $653k

Malaria in pregnant is a public health problem in sub Saharan countries where 11 million pregnancies are exposed to malaria infection. Plasmodium falciparum in pregnant can cause adverse maternal health and poor birth outcomes. Artemisin-based Combination Therapy (ACT) used in treatment of uncomplicated Plasmodium falciparum malaria in pregnant women has the efficacy in Africa. The…

School-aged children based seasonal malaria chemoprevention using artesunate-amodiaquine in Mali National Center for Scientific and Technological Research (CNRST), Mali, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Ogobara Doumbo, Mahamadou S. Sissoko | Mali

Proactive Community Case Management and Child Survival: A Cluster-Randomized Controlled Trial Child Relief International Foundation, Grand Challenges Canada, Johnson & Johnson Foundation, United States Agency for International Development (USAID), University of California San Francisco (UCSF), USA, Malaria Research and Training Center (MRTC), University of Bamako, Mali | Kassoum Kayentao, Nancy S. Padian | Mali

WANECAM is the West African Network for Clinical Trials of Antimalarial drugs. This network is being supported by grants from the European & Developing Countries Clinical Trials Partnership (EDCTP). The WANECAM 2 project aims to accelerate the development of the  Ganaplacide/lumefantrine  combination for the treatment of uncomplicated malaria by conducting clinical trials in four countries…

Clinical evaluation of AntimalarialS tri-therapy with AtovAquone-Proguanil for treatment of uncomplicated malaria in African children (ASAAP) European & Developing Countries Clinical Trials Partnership (EDCTP), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana | Oumou Maiga-Ascofare | Gabon, Benin, Burkina Faso, Guinea, Mali

Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women (PYRAPREG) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Kassoum Kayentao | Dem. Rep. Congo, Mozambique, Burkina Faso, Gambia, Mali