Clinical evaluation of AntimalarialS tri-therapy with AtovAquone-Proguanil for treatment of uncomplicated malaria in African children (ASAAP) European & Developing Countries Clinical Trials Partnership (EDCTP), Kwame Nkrumah University of Science and Technology, Kumasi, Ghana | Oumou Maiga-Ascofare | Gabon, Benin, Burkina Faso, Guinea, Mali
Malaria in pregnant is a public health problem in sub Saharan countries where 11 million pregnancies are exposed to malaria infection. Plasmodium falciparum in pregnant can cause adverse maternal health and poor birth outcomes. Artemisin-based Combination Therapy (ACT) used in treatment of uncomplicated Plasmodium falciparum malaria in pregnant women has the efficacy in Africa. The…
Using single-cell RNAseq to investigate human malaria parasite transmission dynamics Medical Research Council (MRC), UK, Wellcome Trust Sanger Institute, UK, University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Mara K. N. Lawniczak, Abdoulaye Djimde | Africa, Central, Africa, Eastern, Africa, Southern, Mali, United Kingdom
Assessing safety, efficacy and transmission blocking properties of the new anti-malarial KAF156 combined with a new formulation of lumefantrine in children and adults with uncomplicated Plasmodium sp. malaria in West and Central Africa (WANECAM II) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Abdoulaye…
Establishment of an optimized in vitro screening platform for evaluation of antimalarial compounds against liver stages including hypnozoites of Plasmodium vivax and P. ovale using field isolated parasites Medicines for Malaria Venture (MMV), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
Understanding the biology of Plasmodium vivax and Plasmodium ovale for the development of a field-based anti-hypnozoite drug screening model (HypnoBio) European & Developing Countries Clinical Trials Partnership (EDCTP), University of Sciences, Techniques and Technologies of Bamako (USTTB), Mali | Laurent Dembele | Ethiopia, Mali
WANECAM is the West African Network for Clinical Trials of Antimalarial drugs. This network is being supported by grants from the European & Developing Countries Clinical Trials Partnership (EDCTP). The WANECAM 2 project aims to accelerate the development of the Ganaplacide/lumefantrine combination for the treatment of uncomplicated malaria by conducting clinical trials in four countries…